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Urothiliasis
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UROLITHIASIS

Urinary tract Calculi (Stones)

The urinary tract consists of the kidneys, ureters, bladder, and urethra.

Urinary tract calculi otherwise known as stones may occur at any site along the urinary tract.

Stone disease is frequently a recurrent problem as greater than 50% of those with a calculi would have formed another stone within ten years. The risk being much higher in those with metabolic disturbance that are not corrected

The exact causes of kidney stone formation are not completely known; however, hypothesis are that stones are the result of mineral supersaturation and crystallization in the urine. Heredity, environment, age, sex, urinary infection, diet, and metabolic diseases are probably involved in stone formation.

There are factors in food that aid and prevent stone formation. A tipping of the scale towards predisposing factors result in the formation of stone e.g. dehydration leads to the formation of concentrated urine; metabolic diseases, e.g., hyperparathyroidism, cystinuria, gout; infection, primary UGT disease e.g. polycystic kidneys; drugs e.g. loop diuretics that increase levels of uric acid, antacids, vitamin C and D excess, vitamin A deficiency, salicylates etc.

Upper urinary tract calculi are more common in adults than children and are seen more often in men than in women. Bladder stones are rare in women and children, but are common in men due to the greater incidence of lower urinary tract obstruction, e.g., prostate enlargement.

The most common type of urinary stones are calcium, struvite (magnesium-ammonia phosphate), uric acid, xanthine, and cystine. Calcium stones are the most common.

KIDNEY STONES

Kidney stones (calculi) are solid or semi-solid mineral-like substances occurring in the urinary tract.The main problem occurs when the stones block the drainage of the kidney, resulting in urinary obstruction. Urinary calculi are responsible for 10% of urological hospital admissions per year. They also account for a significant number of visits to the hospital emergency departments and absenteeism from work each year

Caucasians are affected more commonly than other racial groups.

Kidney stones are more common in developed .

Clinical features Symptoms of kidney stones may vary from non as in the case of "silent stones" which are those that do not cause any significant urinary obstruction. , to those causing obstruction with excruciating pain. Most obstructing stones, depending upon cause, size, shape, and location, cause the following symptoms:

acute severe pain in the affected side (flank)

nausea and vomiting

hematuria (blood in the urine)

infection

fever


urinary stone medical evaluation?

The medical evaluation will consist of the following:

detailed medical history

physical examination

urine and blood test

kidney x-ray/ultrasound

metabolic stone risk profile

Laboratory X-ray is the chief method used to diagnose kidney stones. Ultrasound can also be used to detect stones and urinary obstruction.

Treatment Treatment centers around medical and surgical; however, the size, location, degree of symptoms, and presence or absence of urinary infection and obstruction influence the treatment decision. Hospitalization is usually necessary for kidney obstruction and infection. A large number of kidney stones are small enough to pass spontaneously. Medical treatment is more successful in prevention of stones than in dissolving them after they have formed.

Medical Treatment:

expectant (observation)

medications

adequate fluid intake

maintaining proper urine pH

diet

Surgical Treatment:

Extracorporeal shock wave lithotripsy (ESWL)

PCN (percutaneous nephrolithotomy-lithotripsy)

Endourology (endoscopic removal or manipulation)

Open surgery

Most stones can be removed without an incision employing the first three surgical treatment procedures. ESWL is one of the most popular techniques today. It works by using shock waves to fragment your stone into small pieces (sand-like) that pass freely through the urinary tract.

Bladder stones

Stones form in the bladder due to outflow obstruction ( urethral strictures, prostatic obstruction) and the presence of foreign body e.g. in-dwelling catheter. Some stones found in the bladder may have been formed in the upper UGT

Clinical Features

Most people with stones are usually without symptoms, however, pain is the most common symptom which may be sharp, dull, intermittent or colicky. Increase in fluid intake or exercise causes an increase in the pain both via causing increase movement of the stone.

Ureteric stones cause severe colicky abdominal pain that radiates towards the groin. Haematuria often occurs. The presence of infection may present with frequency, dysuria or haematuria. Rarely, a stone at the bladder neck may cause outflow obstruction resulting in urinary retention.

Investigation

Plain abdominal X-ray and IVU

Unehanced helical CT.

All above, in combination, will help in elucidation of the stone be it radiolucent or opaque. Stones may appear as filling defects. Obstruction will be observed as failure of flow of contrast material.

Treatment

Analgeics.

Stones less than 5mm usually pass out spontaneously, those greater than 1cm usually require intervention. Intervention is also required if a stone is not moving and causing partial obstruction in the absence of infection.

Extracorporeal Short Wave Lithotripsy

Nephrolithotomy

Open surgery.

Ureteral stones
A ureteral stone is actually a kidney stone that has moved into the ureter and can be an extremely painful condition. However if small enough, the stone will pass through the urine with some or no pain. As the stone grows, it can obstruct urine flow and become lodged in a narrow part of the ureter. The most common symptom is a sharp pain in the back or side, or possibly the lower abdomen. Symptoms may also include nausea, vomiting, or blood in the urine. Typically, initial management involves drinking lots of fluids to cause the stones to exit the body with the urine. In more severe cases, where the stones have become too large, or other treatment has not worked, surgery to remove the stones may be necessary.

Investigations are as above.



 
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